Colorectal cancer (CRC) remains a major global health challenge characterized by high incidence and mortality rates. Emerging evidence supports the use of plant-derived bioactive compounds as promising agents in cancer therapeutics. This study aimed to assess the anticancer potential of phytoconstituents from Moringa oleifera, Olea europaea, Brassica oleracea, and Vitis vinifera against key colorectal cancer protein targets using in silico methods. Phytochemical constituents from these plants were compiled from literature and chemical databases, with their three-dimensional structures retrieved from PubChem. Target proteins implicated in colorectal carcinogenesis, including Human Thymidylate Synthase enzyme, 1HVY, and epidermal growth factor receptor (EGFR), 1XKK, were prepared for docking using Biovia discovery studio. Molecular docking simulations were performed with AutoDock Vina in PyRx, evaluating binding affinities and ligand interactions at active sites. Post-docking analysis and ADMET predictions were done using Biovia discovery studio and ADMETLAB, respectively.

This study investigated the growth performance of African catfish (Clarias gariepinus ) fry raised with a commercial feed (Coppens) and a farm made feed. Three treatments were used with three replicates per treatment. A total of 1800 fry were obtained and the experiment was conducted for a period of four weeks using experimental plastic bowls, with 200 fry per bowl. The water quality parameters (Temperature, pH, Ammonia content, Dissolved oxygen) were recorded and were within acceptable range. The effects of different diets on specific growth rate (SGR), survival rate (SR) and feed utilization were determined. Among the various experimental feeds, Treatment 1(Coppens) produced a better result compared to the others in terms of weight gained and specific growth rate. The lowest growth performance was with fry in Treatment II (Fry fed farm made feed). Estimated cost of feeding was higher in farm made feed and combined feed (N5,260), with lowest values occurring in fry fed with it Coppens (N4,600). During the experiment Coppens performed better than the other experimental feeds, it showed a higher survival rate and low pollution level. It also showed a better feed
utilization and the highest performance index..

The purpose of this study was to evaluate the Anyi field's seismic volume in order to provide the best structural frameworks for the D5000 reservoirs, which would be utilized to create precise static models. Using fault representations and depth-converted surface maps, the reservoir's structural model was built. There are two main East-West oriented faults that define the reservoir's structural structure. The Amosi growth fault borders it to the north, while the Klin boundary fault borders it to the south. It is structurally an elongated rollover anticline that is oriented east-west. Channels and shorefaces make up the majority of the reservoir. The data was revalidated and quality-checked, and a thorough literature study was carried out. A MADCOW bandpass filter was used to reduce both coherent and random noise in the seismic data. Well-toseismic calibration was then performed utilizing Anyi-001's sonic log. They interpreted the fault and horizon. Checkshots from Anyi-006, from which the time and depth map was constructed, were used to simulate velocity. Amplitude extraction was then used to improve seismic visualization and find characteristics or anomalies associated with reservoir characteristics, including fluid connections, channels, fractures, and changes in porosity. The results of this investigation indicate that the D5000 reservoir has a limited potential for hydrocarbon recovery and accumulation in the Anyifield (Anyi-006) but a high potential in the Okoko field (Okoko-001). In order to maximize gas recovery from this significant reservoir, the results provide a better knowledge of the stratigraphic disposition of the reservoir, which will aid in better interpretation, lower drilling risk, and well-informed economic decisions. Additionally, this study's results confirm that seismic interpretation, velocity modeling, and attribute analysis techniques are trustworthy and efficient means of evaluating the Niger Delta's reservoir features and volumetric analysis

Heterocyclic compounds are very widely distributed in nature and very abundant in plant and animal products. They are included in many biochemical materials essential for life like nucleic acids (nucleotides), sugars and their derivatives, vitamin C and also, most members of vitamin B group (vitamin B6- pyridoxine). They are also found in application of diverse field such as agriculture, pharmaceutical and manufacturing industries. Researches have shown that heterocyclic nuclei give high chemotherapeutic values such as anti-malaria, anti-diabetics, anticancer and also act as a remedy for the development of novel drugs. Imidazole containing moiety occupied a unique position in organic compounds. It is a five-membered nitrogenous heterocyclic moiety that has three carbons, two nitrogens, four hydrogen atoms, and two double bonds having general molecular formula of C3H4N2. It is also known as 1,3-diazole because of the nitrogen atoms present at the first and third positions (non–adjacent position) of the ring, one nitrogen bear a hydrogen atom as the pyridine structure, and the other is called pyrrole type nitrogen
and position four and five are equivalent. It formed the basis of many therapeutic natural products such as histamine, purine, histidine among others

This study was to carry out a comparative study on the impact of social on the political mobilization and public opinion: a case study of the Nigerian 2023 presidential election. The study was necessary to examine how impactful social media was on political mobilization and public opinion a case study of the Nigerian 2023 presidential election. The study adopts the investigative survey research method. The research instrument was a well-structured questionnaire. The questionnaire was validated by the project supervisor for final correction. The reliability test was carried out using the test re-test method to arrive at a value that was reliable. Questionnaires were administered and answers offered were collated and analyzed using the frequency count, mean and standard deviation, while regression analysis was used to test for hypothesis. Findings from the study revealed that social media was impactful on the political mobilization and public opinion a case study of the Nigerian 2023 presidential election, it will help ordinary Nigerians understand how social media affected the 2023 presidential election; it will reveal both negative and positive effects of social media on political mobilisation and public opinion

Cervical cancer is the fourth most frequently diagnosed cancer among women worldwide, with nearly 90% of new cases and related deaths occurring in low- and middle-income countries. This study examined the knowledge, attitudes, and practices related to cervical cancer prevention among female students in the Faculty of Social Sciences at the University of Benin, Nigeria. A descriptive cross-sectional survey was utilized, and 315 participants were selected through a proportionate stratified random sampling approach.Findings showed that the respondents possessed a moderate level of knowledge about cervical cancer, particularly regarding its definition, modes of prevention, and transmission. Although attitudes toward screening and preventive measures were largely positive, many students reported not engaging in any form of preventive practice. The study also established a statistically significant association between students’ knowledge levels and their preventive practices (χ² = 31.17, p < 0.0001).Overall, the results underscore the need for focused educational strategies aimed at improving young women's awareness, attitudes, and engagement in cervical cancer prevention activities.

The study examined the relationship between quality assurance and internal efficiency of primary school teachers in Oredo Local Government Area Edo State. The study was a descriptive research design of the survey type. The study population This study involves the
assessment of internal quality assurance practices in school the population of the study was a total eight six (86) Primary school in the 3 zones in Oredo Local Government Area Edo State The sample of this study comprised of one hundred (100) teachers drawn from five (5) Primary school from each of the 3 zone in Oredo LGA of the Benin metropolis, using the simple random sampling technique. All members were drawn randomly at the various zone where the
respondents were approached for participation in the study. It was also revealed that there was significant difference in the quality assurance measures provided in rural and urban schools. It
was concluded on the basis of the findings of the study that quality assurance is an essential variable of primary school teachers’ internal efficiency. It was therefore recommended that supervising agencies of primary education should closely monitor teachers’ activities, especially those in the rural areas in order to boost their internal efficiency. It was also recommended that workshop and conferences should regularly be organized for primary school administrators, most especially those in the rural areas on the various ways through which their teachers’ activities could be monitored in order to actualize school goals

The logistics monitoring system, developed as a university project, seeks to enhance resource management and transportation logistics. It offers real-time tracking of assets and facilities, facilitates efficient coordination of transportation services, and provides comprehensive reporting and analytics for informed decision-making. By improving efficiency and transparency, the system contributes to enhancing operational effectiveness, benefiting various stakeholders involved.

The pipelines that transport petroleum products across Nigeria are vital for the country’s economy and energy security. However, they are also exposed to various hazards and risks, suchas theft, sabotage, corrosion, impact damage, fire, explosion, and environmental pollution. Theserisks can cause significant losses of life, property, and revenue, as well as damage the reputationand credibility of the pipeline operators. Therefore, it is essential to conduct a hazard andoperability (HAZOP) study and a risk assessment of the pipelines to identify the potential causesand consequences of failure, and to propose appropriate mitigation measures. A Hazard and Operability (HAZOP) analysis of pipelines is a systematic and structured processused to identify potential hazards, operability issues, and risks associated with the design, operation, and maintenance of pipeline systems. This report presents the methodology and results of a HAZOP study and a risk assessment of thepipelines across Nigeria. The report also reviews the existing literature on the topic and
compares the findings with the data collected around the pipelines observed in around EdoState. The report also went ahead to calculate the third party damage index for some selected pipelinesand examines the pipeline right of way conditions in such locations. The report aims to provide useful information and recommendations for the pipeline, regulators, stakeholders, and researchers who are involved or interested in the safety and reliability of thepipelines across the State.

Musculoskeletal disorders (MSDs) are a common occupational hazard among nurses, primarily due to the physically intensive nature of their duties. These disorders negatively affect the health, productivity, and quality of life of healthcare workers. In tertiary healthcare institutions, the workload and physical demands can vary significantly across different specialty areas, potentially influencing the prevalence and pattern of MSDs. This study aimed to assess the prevalence, types, and associated risk factors of musculoskeletal disorders among nurses across various specialty units in a tertiary healthcare institution in Benin City, Edo State. A descriptive cross-sectional study was conducted among nurses working in specialty units such as emergency, intensive care, surgery, internal medicine, pediatrics, and obstetrics and gynecology. Data were collected using a validated, self-administered questionnaire adapted from the Nordic Musculoskeletal Questionnaire. Descriptive and inferential statistics were used to analyze the data and identify significant associations. The findings revealed a high prevalence of MSDs among nurses, with the most affected body regions being the lower back (72%), neck (55%), and shoulders (48%). Emergency and intensive care unit nurses reported the highest incidence of MSDs. Key risk factors identified included manual lifting of patients, prolonged standing, awkward postures, and insufficient staffing. Nurses with longer years of service and those lacking ergonomic training were significantly more affected. Musculoskeletal disorders are widespread among nurses in this tertiary healthcare institution, with noticeable variations across specialty areas. There is a critical need for ergonomic interventions, routine training, and improved staffing policies to reduce the burden of MSDs among nurses