2023

Rising incidences of benin and cancerous tumours, such as benign prostatic hyperplasia (BPH)
and prostate cancer, coupled with the unpleasant side effects of current therapy, suggest a need to
search for new drug molecules. The stem bark of Lonchocarpus griffonianus G. Don
(Fabaceae) is an important medicinal plant used in Nigeria to treat BPH and other tumour
related ailments. No pharmacological study on the use of the plant for treating BPH has been
reported. This study aimed to investigate the protective effect of L. griffonianus (LG) on BPH.
Two organs (stem and root barks) of LG were identified, collected, pulverized and extracted with
absolute methanol (99 %) using a Soxhlet extractor. Comparative preliminary biological
evaluations were done on the L. griffonianus stem bark (LGSB) extract and root bark (LGRB)
extracts using two benchtop assays (cytotoxic and antiproliferative). The acute toxicity of the LG
stem bark extract was done using a modified Lorke's method. The extract was subjected to
Vacuum Liquid Chromatography (VLC) and Gravity Column Chromatography (GCC) to obtain
two isolated compounds, LO1 and LO2. The compounds were subjected to MS and 1D NMR
analysis for identification. The isolated compounds (LO1 and LO2) were subjected to cytotoxic
evaluation on human prostate (PC3) and uterine cervical cancer (Hela) cell lines using a 3-(4, 5
dimethyl thiazolyl-2)-2, 5-diphenyltetrazolium bromide (MTT) assay. Anti-BPH evaluation was
done on the extract and LO1 using testosterone-induced BPH in the rat model. BPH was induced
by the administration of testosterone propionate (4 mg/kg, s.c., in olive oil) for 28 days. LGSB
extract (100, 200 and 400 mg/kg), LO1 (5 mg/kg), LGSB extract (200 mg/kg)+finasteride (5
mg/kg) and finasteride (5 mg/kg) were orally administered daily. On day 29, the rats were
sacrificed under anaesthesia and blood was collected via the abdominal aorta. The collected
blood was centrifuged, and the serum was separated. The serum was analyzed for biochemical
parameters such as prostate-specific antigen (PSA), testosterone and estradiol. The prostate was
harvested for histological examination. The wet weight and volume of the prostate were taken.
The prostate index (PI) was calculated. All data were expressed as mean ± SEM (standard error
of the mean) and were compared using analysis of variance (ANOVA),The result of preliminary evaluations indicated that the LGSB extract has a higher activity (100 ±0.00% mortality at 80 µg/mL) than the LGRB extract (3.33 ± 1.29% at 80 µg/mL). Acute
toxicity results revealed no mortality in both phases after oral administration with LD50>5000mg/kg. LO1 and LO2 significantlyinhibited the multiplication of PC3 and Hela cells in vitro

The Edo people of Nigeria have a rich cultural heritage and their traditional marriage are marked by variety of songs and rituals that carries significance meaning. This project aims at conducting a semantic review of the songs and rituals use in the Edo traditional marriage ceremony through an interdisciplinary approach that combines linguistics analysis, and cultural interpretation. This study seeks to explore the linguistic, cultural, and social dimensions of these songs and rituals by delving into the lyrics of the songs and also by analyzing the symbolic significance of various rituals. This study employed data collected from participation observation at a selected traditional marriage in Benin using a phone camera, and also the interviews of native speaker who are well grounded in the Edo marriage rituals. In analyzing the marriage song, the difference level of translation will be use to analyze the lyrics of the songs. By the end of this research

This study examined the survey on the teaching methods of teaching poetry in junior secondary schools. In order to achieve the intended objectives of the study, three research questions were raised. The descriptive survey research design was employed for the study. The population of the study was made up of all junior secondary school students in Egor Local Government Area of Edo state. Hundred students were randomly drawn from five schools in Egor LGA of Edo state. A questionnaire was used for data collection. The data collected from the questionnaire were analyzed using descriptive statistics such of frequency, percentage, and mean . The findings showed that that the teaching method used in teaching poetry in secondary schools are effective, teachers use a mixture of different methods which includes recitation, traditional method, creative writing and guided reading and annotation when instructing poetry to Junior Secondary School students and students' English understanding affect their ability to understand poetry, lack of connection between daily life and poetry affect how much students like and understand it and culture can help students understand the hidden meanings in poetry. The following recommendations amongst others were made; Provide ongoing professional development opportunities for English teachers, specifically focusing on enhancing their skills in utilizing diverse teaching methods. This could include workshops, seminars, and training sessions to keep teachers updated on effective strategies for teaching poetry

Refractive errors, including myopia, hyperopia, and astigmatism, constitute a significant public health concern affecting visual well-being of individuals as well as the academic performance of pupils. Uncorrected refractive error, the second most common cause of preventable blindness globally places a heavy burden on individuals and the society. This study aimed to assess the knowledge, attitudes, and practices of refractive errors among secondary school students in Egor Local Government Area (LGA). The study was carried out for a period of three month. A stratified random sampling method was used where students from the selected schools within Egor LGA were selected for the study. The sample size was 400 with a number of 151 females and 249 males. Data was collected using a well structured self-administered questionnaires. This questionnaire included demographic information and was further divided into three sections. The data collected were analyzed using the statistical package for social sciences (SPSS) version 22.0. Descriptive statistics (frequencies, percentages, mean and standard deviation) was used to
summarize the variables. Continuous variables was expressed as the mean ± standard deviation for those that displayed normal distribution. A total of 400 students participated in the study between the ages of 11 to 19years (mean age 16.07± 1.320). Majority of the participants was male (249) while the remaining where females (151). The results showed that those who had good knowledge about refractive errors was about 52.3% while those who had good attitudes to refractive errors was 44% and who with good practice of refractive errors was just 17.5% of the
respondents. In conclusion, the knowledge about refractive error was fair, attitude towards refractive error was good but the practices towards refractive error was poor.

In an increasingly digital world, User Interlace (UI) and User Experience (UX) design have become pivotal in shaping the interactions between users and technology. This comprehensive study delves into the multifaceted realm of UI and UX design, aiming to unravel the intricacies and importance of crafting intuitive and user-centric interfaces. Through a meticulous exploration of principles, methodologies, case studies, and emerging trends, this study seeks to provide valuable insights for designers, researchers, and stakeholders in the field. By examining the symbiotic relationship between UI and UX, we aspire to illuminate the path towards creating memorable and meaningful digital experiences

The study examined job satisfaction as motivational tool for increased productivity. Four research objectives were raised to carryout the study, the four specific objectives were to: know what makes job satisfaction a motivation tools for increased productivity; Identify the various tools methods used to measure job satisfaction and the impact on productivity among employees; explore the factors that contribute to employee satisfaction and their potential to drive productivity improvement at work and examine the conditions and workplace factors that lead to employee dissatisfaction, with the goal of identifying areas for productivity enhancement. The research was limited to the selected organization(s) name Nadia enterprise in Benin City, Edo State. The population of this study is made up of all the staff in Nadia Enterprise. The study covers all groups and cadre of staff in the Organization. The population stands at 85 staff in the Organization being composed of professionals and non-professionals. The absence of a sampling technique in the questionnaire administration for this study was attributed to the insufficient staffing levels at Nadia Enterprise. The staff at Nadia Enterprise is relatively small or homogeneous in terms of characteristics relevant to the study, using a sampling technique may not yield substantial benefits. Computed frequency distributions, averages, modes, range and percentages was used to draw inferences on the degree of occurrence of the variables measured within our study sample. It was concluded that a substantial proportion of respondents recognize a positive relationship between job satisfaction and both employee motivation and increased productivity. Furthermore, the majority of participants underscore the pivotal role of recognition and appreciation in enhancing job satisfaction, ultimately leading to improved productivity. Based on the findings and conclusion the researcher then give the necessary recommendations.

This study focused on effect of Covid-19 on market orientation of catfish farmers in Ikpoba-Okha Local Government Area of Edo state Nigeria. The specific objectives were to : describe the socioeconomic characteristics of catfish farmers; identify the farming activities engaged in by the respondents; examine the measures used by catfish farmers to maintain market oriented production during outbreak of Covid-19 in the study area; examine the market orientation level of the catfish farmers during the outbreak of the Covid-19 ; ascertain the effect of the pandemic on the market orientation of the respondents ; identify the marketing information sources used by the respondents during the pandemic and identify the constraints encountered by the respondents during the outbreak. A three-stage sampling procedure was used for a proportional randomselectionof124 catfish farmers from the four fish farm clusters in the Local Government Area of the study. Primary data was collected through the use of structured questionnaire in line with the objectives of the study and was supported by in person interview schedule conducted among catfish farmers. Data was analysed using descriptive statistics such as frequency counts, percentages and mean scores as well as inferential statistics such as Multiple regression analysis

The Implementation of electronic health records (EHRs) has gained significance in improving healthcare delivery globally. This study aims to conduct a comparative study on the implementation of EHRs in the private and public sectors for health care delivery in Edo state, Nigeria. The general objective of this study was to assess the role and implementation of electronic health record to selected private and public sector for healthcare delivery in Edo state. The research was to explore the current state of EHR implementation in both sectors, identify the barriers and challenges faced during implementation, and analyze the impact of EHRs on healthcare quality and efficiency in Edo state. A mixed-methods research approach was employed, incorporating quantitative data collection through surveys and qualitative data collection through interviews and focus. The findings of this study will provide valuable insights into the strengths and weaknesses of EHR implementation in the private and public sectors in Edo state and will inform policymakers and healthcare professionals on best practices and strategies to maximize the benefits of EHR adoption for improved healthcare delivery in Edo state, Nigeria. Specifically, it recommended that the selected health institutions both public and private should ensure the availability of finances, adequate staff training in the technical know-how of the technological advancement, also be technical infrastructures and manpower like electronic record managers, ICT support staff and computer medical devices. This research will contribute to the existing literature on EHR in the context private and public health care delivery in Edo state and Nigeria, where few research has been conducted on this topic.

Stroke is a leading cause of death and disability worldwide. This study was conducted to investigate the prevalence of stroke and it's associated risk factors among patients admitted at the neurological ward of University of a tertiary health facility. The objectives this research work aims to determine the prevalence of Cerebrovascular accident, identify the associated risk factors, determine the percentage of stroke survivors and distribution of mortality rate. The study employed a retrospective descriptive survey design method. The area of study was the neurology
ward in the University of Benin Teaching hospital, Benin City, Edo State, Nigeria. Of a total population of two thousand three hundred and thirty-nine patients admitted, one thousand three hundred and ninety-seven patients were diagnosed of CVA and their data was collated. Purposive sampling technique was used. A well-structured checklist was used to elicit items relevant to the research objectives. The study showed that the prevalence of CVA was 58.9% of the total population, and the most prevalent risk factors were hypertension and diabetes mellitus. The percentage of survivors was 69.4% and the distribution of mortality was highest amongst the males, age group 50-69, married patients, tertiary level of education, Christians, and Bini. The study therefore recommends that community education on lifestyle modifications, beneficial nutritional practices, maintaining appropriate body weight should be ensured. Also health workers should make anthropometric measurements, blood pressure and blood glucose level a routine procedure to ensure prompt treatment and eradication of these risk factors.

In this discourse, the relevane of building Development Communication intervention on establish models of communication ot achieve maximum benefits from such intervention is highlighted. It borrowed from posiont of communication models such as the objective or transmission model. Subjective or receiver-oriented model and the social network or negotiation model. Important considerations to make the most of Development Communication interventions are also x-rayed. This include among others sing development communication as participatory tool for agriculture nad rural development, seeing it as worthwhile venture and not mere megaphone of development interventions, its usefulness for varied development intervention an seeking the service of trained development communication specialists,