Erectile dysfunction, a prevalent issue among men today, is characterized by difficulties in
achieving or maintaining a firm erection during sexual activity. While drugs like Viagra (a
phosphodiesterase-5 inhibitor or PDE5) are available, they often come with side effects like
headaches, dizziness, and vision problems. This research aims to identify the the bioactive
compounds in plants traditionally used for treating erectile dysfunction. Phytoconstituents from six plants Cyperus esculentus tubers, Piper guineense leaves and seeds, Spondias mombin leaves and fruit, Tamarindus indica fruit and seeds, Terminalia catappa seeds, and Rauwolfia Vomitoria leaves and roots were obtained from literature and their 2D strructure
data file (SDF) were retreived from PubChem. The phytoconstituents and the stanadards
sildenafil and tadalafil were docked with Phosphodiesterase enzyme (2H42) using PyRx after it
was prepared with chimera. Post docking analysis, Absorption, distribution, metabolism and
excretion (ADME) and toxicity profile were carried out using Biodiscovery studio, swissADME
and admetSAR software respectively. The results showed varying binding affinities of the compounds for PDE5 drug targets
comparable to the standards (≥-9.8 kcal/mol). Most of the hit compounds exhibited potential as
drug leads for use in erectile dysfunction. Lanosterol from Cyperus esculentus, Thujopsene from
Piper guineense, Lupenone from Spondias mombin and Tamarindus indica, while
Spiro[Androst-5-Ene-17,1'-Cyclobutan]-2'-One, 3-Hydroxy-,(3.Beta.,17.Beta.)- for Rauwolfia
vomitoria demonstrated the strongest binding affinity with -11.1, -10.9, -17, -18.9, and -10.9
respectively. Many of the constituents showed good therapeutic potential for the treatment of erectile
dysfunction. However, further studies such as molecular dynamic simulation, in vivo and in vitro
studies need to be carried out to further validate the claim.

This study examines biology teachers’ willingness to integrate Information and Communication
Technology (ICT) into their instructional practices, identifying key barriers and enablers to
adoption in secondary schools. A descriptive survey design was employed, with data collected
from thirty (30) biology teachers across schools, using a Likert-scale questionnaire. Findings revealed strong teacher willingness, with high enthusiasm for ICT tools and peer
advocacy. However, systemic challenges particularly unstable electricity, inadequate school
infrastructure, and insufficient training significantly hindered implementation. Teachers
proposed actionable solutions, including regular subject-specific training, dedicated technical
support teams, and biology-focused ICT tools. The study concludes that while biology teachers are predisposed to adopt ICT, transformative
integration requires targeted interventions addressing infrastructure deficits, professional
development, and curricular flexibility. These findings contribute to the Technology Acceptance
Model (TAM) by contextualizing its constructs within resource-constrained educational settings. Recommendations are provided for policymakers, school administrators, and teacher training
programs to bridge the gap between willingness and effective ICT adoption.

This study investigated the perceived influence of study habits on academic performance of business education student. Five research question were raised in this study. This bothered on how study habits influence academic performance.

Descriptive survey design was used in carry out this study. The target population was 166 students of business education which comprises of this 3 levels 100, 200 and 400 level, 300level was exempted because of their non-presence at the time of research. The sample size of this research is 50% of the total population. The questionnaire was the instrument of this data collection. An analysis of data was done using mean score and standard deviation. From the result of the findings, the study revealed a significant relevance of study habits influencing the academic performance. It was also concluded that there is high extent to which study habits influence academic performance of business education students.

Based on the findings of this study, the researcher recommended that;
Business education teachers should teach the student on how to take important notes during every lesson. By so doing, the students would develop good habits of note taking and this could lead to good academic performance. For guidance counselors and school administrators, it is advised that they make interventions and monitor the student’s progress regarding their study habits and academic standing. They should hold seminars about forming good study habits or administering diagnostic tests and create a workable solution to help the students determine what study habits are effective for them. For parents/guardians, it is recommended that they actively partake in their children’s development regarding their academic journey. They should make an effort to know what study habit best work for their children so that they can work towards supporting them and providing them with an appropriate and adequate study environment. Doing so could help their children focus on their education and ultimately form good study habits

The illocutionary acts of the main character's utterances in Wumi Raji’s Another Life reveal various communication strategies and attitudes. The study analyzes 137 illocutionary acts, categorizing them into four types: 54 representative acts (40%), 59 directive acts (43%), 10 commissive acts (7%), and 14 expressive acts (10%). The directive acts are the most frequent, indicating the main character's active role in communication, while the expressive acts reflect personal feelings and attitudes. This analysis contributes to understanding the speech act theory, which emphasizes the interaction between language and behavior, highlighting how language can express intention and action. For a deeper understanding, you can refer to the detailed analysis in the provided sources.

The effect of malaria in our present day society on pregnant women continue tohaveadverse effect on their health and that of the baby. The study investigated the Knowledge of theeffect of malaria on pregnant women among antenatal women in University of Benin TeachingHospital (UBTH). Benin City, Edo State. A descriptive survey was employed in this study. Four (4) research questions were raisedto guide the study. The population of the study comprises of all pregnant women in the
University Of Benin Teaching Hospital (UBTH) with a total population of seventy- six (76), theentire population was used as a sample size. A structured questionnaire was used for data
collection. The questionnaire was validated by the researcher's supervisor and one other expert inthe Department of Health Safety and Environmental Education; while the test- re test reliabilitymethod was adopted to ascertain the reliability of the instrument. Data collected were analyzedusing mean and standard deviation. findings one revealed the level of knowledge of pregnant women about malariaprevention. Research question two revealed the level of effect of malaria on pregnant women. The knowledge of the effect of malaria helps provide awareness among pregnant, enhancepregnant women health, attitude towards malaria, promote health situations facilitate healthful
relationship and enables pregnant women make responsible decisions and concerningtheknowledge of the effects of malaria.

Herbal extracts which can serve as medicinal plants have been used since ancient times and
even considered the source of modern medicine. Bryphullum pinnatum extracts have been
shown to possess neuroprotective properties potentially useful in treating neurodegenerative
diseases. Bryophyllum pinnatum is a plant used to treat inflammations, infections, and also
have anti cancer properties. This study was carried out to explore the effects of Bryophyllum
pinnatum extract on the cerebrum of Adult Wistar rats.A total of thirty (30) rats weighing
between 140g-200g were randomly assigned into six (6) groups (A,B,C,D,E and F),with five
rats per group. Group A was control group while Group B,C,D,E and F were administered
with Bryophyllum pinnatum extract in doses of 200,400,600,800 and 1000mg/kg
respectively.The rats were acclimatized for a period of two weeks and administered for a
period of four weeks using oral route by the use of orogastric tube. The rats were
anesthesized with chloroform and then sacrificed. The cerebrum was harvested and
immediately fixed for antioxidant stress test and for tissue processing. H&E stains were used
for histological test. The result of the study shows that there was no statistically significant
difference (P<0.05) in the final body weight of rats in entire group compared to it's initial
body weigh except group B where there is a significant change in weight .There was no
statistically significant difference (P<0.05) in cerebrum weight and organo-somatic index. In
the chart showing the antioxidant results, it shows that it is not statistically significant. Histological slides in control group show: molecular, external granular, external pyramidal, internal granular, internal pyramidal and multi-form layers. Group B show: vasodilatation
normal pyramidal neurons with conspicuous nucleoles oligodendrocytes and neuropil. Group
C show: normal neurons with conspicuous nucleoles, oligodendrocytes, neuropril cerebral
vasodilatation. Group D show: normal granular cell neurons with conspicuous nucleoli, normal oligodendrocytes and marked vasodilatation and active congestion. Group E and F
marked show vasodilatation and active congestion, normal granular cells with conspicuous
nucleolus and oligodendrocytes. In conclusion, graded concentration of Bryophyllum
pinnatum induced vasogenic effects and increased protein synthesis in a dose dependent
fashion and it had no adverse effect on it.

This research work was designed to find out the effects of class size on teaching and
learning in pre-schools in Oredo Local government area of Edo state. Four research
questions were raised to carry out this study and to effectively carry out this research, a
total of 100 respondents were sampled from the 66 registered pre-primary schools in the
Local government area. The instrument used to carry out this research is checklist and
questionnaire. This study revealed that the classrooms allocated for pre-primary
education in schools were in deficit to cater for the population of pupils being enrolled, there were not enough instructional materials and teaching aids due to overcrowding and
limited resources. Based on these findings, it was concluded that evidently, class size is a
major variable that has impacts on the overall teaching and learning process in pre- schools. Recommendations were made to ensure the effectiveness of teaching and
learning in pre-schools and this includes: investing in infrastructure e.g classrooms, child
sized furniture etc, employment of only qualified teachers and personnel, availability of
teaching aids in adequacy to the population of pupils, intervention of the government and
educational bodies to carry out supervision and assessment of the conditions of
preschools that are operating in the area.

During the period of rapid spread of the corona virus infection, a large number of infected were
quarantined and otherwise isolated from the general populace. Face to face access to such people
was risky and difficult. Even medical personnel had to take stringent and inconvenient measures
to safeguard themselves, before they could meet physically with such patients. Arising from this,
the aim of this work is to design and construct a telepresence robot that will help to monitor, and
communicate with an isolated person.
The proposed system makes use of a mobile platform driven by four electric motors, with each
driving wheels for precise navigation control. The motors are controlled by an L298N motor
driver. The system also makes use of central microcontroller with WIFI capabilities to establish
connection with a smart phone using the Adafruit IoT (Internet of Things) interface. It also has a
12V lead acid battery for supplying power. The power supplied by this battery is regulated and
stepped down to 5V by an Lm7805 voltage regulator and this voltage regulator supplies power
directly to the micro-controller and the motor driver (or controller)
The system performed as required. The robot successfully connects to the internet and responds to
commands given through the IoT platform. Motors responded correctly to commands, rotated in
the specified direction, and at the desired speed. The motor control system is functioning properly,
and the robot can move as intended. The robot can transmit a clear and stable live video feed with
minimal lag. However, when the internet connection is poor, the video feed becomes blurry,
pixelated, or experiences frequent interruptions

The perception of insect pests management methods in rural areas of Badagry Local Government Area, Lagos State, Nigeria, is a critical aspect of sustainable agriculture and community well-being. This abstract provides a concise overview of a study conducted to understand the prevailing attitudes and beliefs of rural farmers towards insect pest management. In rural Badagry, agriculture plays a pivotal role in livelihoods, making insect pests a significant concern. This research employed a mixed-methods approach, combining surveys and interviews to gather data from farmers and agricultural extension officers. The findings reveal a complex perception landscape, where traditional and modern pest management methods coexist. Farmers, deeply rooted in tradition, often rely on indigenous knowledge and cultural practices. However, awareness of modern, science-based pest management approaches is increasing, thanks to the efforts of agricultural extension officers and outreach programs.Challenges such as limited access to resources, information gaps, and economic constraints affect the adoption of modern methods. Attitudes towards chemical pesticides are mixed due to concerns about environmental and health impacts. Furthermore, climate change is altering the pest landscape, necessitating adaptive strategies. This study underscores the importance of bridging the gap between traditional and modern insect pest management practices. It advocates for holistic, context-specific interventions that consider local knowledge while promoting sustainable, science-based approaches. Such initiatives can enhance food security, reduce pesticide risks, and support the resilience of rural communities in Badagry and similar regions.

ABSTRACT
Social media in enhancing corporate communication in bank especially in Guaranty Trust Bank can be seen as an integrated approach to achieving organizational study. This research work looked into the public relations practitioners assessment of the use of social media in performance of communication activities of access and Guaranty Trust Bank in Benin city, how it harnesses the huge corporate communication. The main source of data used in this research is both primary and secondary data. Secondary data consist of data from already published materials such as textbooks, journals, the internet, academic dissertation, workshop papers and annual reports. Primary data was collected through the means of questionaire. This consist of data collected from the field survey. This source of data formed the basis of analysis in this study. The research established the important of social media in corporate communication within the two mentioned bank, which are Access and Guaranty Trust Bank. It confirmed the support given to corporate communication by public relations practitioners through the engagement of social media in bank. It also emphasize the benefit of social media in the banking industry by public relations practitioners.