PREVALENCE

Intestinal parasitic infections (IPIs) remain a significant comorbidity among individuals living with HIV/AIDS, particularly in resource-limited settings. This study assessed the prevalence and distribution of intestinal parasites among HIV/AIDS patients attending ART clinics at a secondary health facility in Benin City. A total of 150 patients were recruited and stool samples were examined microscopically.Sociodemographic,clinical,andhygienerelated data were also collected using structured questionnaires, and associations were analyzed using chi-square tests.. The overall prevalence of intestinal parasites was 28.7%. The most frequently detected species were Entamoeba coli, followed by Entamoeba histolytica, Ascaris lumbricoides, and Trichuris trichiura. Prevalence was higher among females than males in both hospitals, with a statistically significant association (p = 0.042). Rural residence was also significantly associated with infection (p = 0.001). Other factors, including age, marital status, education, occupation, and hygiene practices, showed variations but no significant statistical associations. Widows and patients with tertiary education recorded disproportionately higher prevalence, while inconsistent hand washing, irregular deworming, and animal contact were linked with increased infection risk,though not statistically significant.IPIs remain common among HIV/AIDSpatients in Benin City despite ART availability. Gender, rural residence, and socioeconomic vulnerabilities contribute to the persistence of infection. Routine stool screening, targeted deworming, gender- sensitiveinterventions, and improved sanitation in rural areas are recommended to reduce the burden of parasitic co-infections and improve HIV treatment outcomes.

Opioids are a class of drugs naturally found in the opium poppy plant, Papaver somniferum. It refers to compounds that are extracted from the poppy seed (e.g morphine) as well as semi synthetic and synthetic compounds with similar properties (e.g fentanyl) (WHO, 2021). The term opioid is used to refer to all compounds that bind to opiate (opioid) receptors. Opioids are alkaloids that are directly derived from the opium poppy plant and the name “Opiate” can be used to describe them. Among these alkaloids are codeine and morphine. Opioids include synthetic opioids like methadone, fentanyl and propoxyphene as well as semi-synthetic opiates, which are medications made from naturally occurring opiates (such as heroin from morphine and oxycodone from thebaine). Narcotic is a legal term used to describe opioids and a few other drugs that are grouped with the opioids by law enforcement hence, it should not be used in the clinical setting (Naidu et al, 2015). Opioids have a number of impacts on the brain including numbing of pain. They work by attaching to opioid receptors on the cells of the brain. These cells send out signals that cause massive amounts of dopamine to be released throughout the body, thereby reducing the experience of pan and increases feelings of pleasure

The World Health Organization (WHO, 2021) defined Cardiovascular Diseases (CVDs) as a group of disorders of the heart and blood vessels. CVDs include coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other conditions. And are the leading cause of death globally, causing, -an estimated 17.9 million deaths in 2019 alone, which represents 32% of all global deaths. Heart attacks and strokes account for more than four out of five deaths from CVDs, about of which one-third of these deaths happen prematurely among adults under the age of 70 years (World Health Organization, 2021). In Africa, Non-Communicable Diseases (NCDs), particularly CVDs, are highly prevalent (Minja et al., 2022). In addition to contributing to 22.9 million Disability- Adjusted Life Years (DALY) and 38.3% of fatalities associated with NCDs, CVDs have the highest burden among those under 30 years. Currently, the burden of CVDs has increased by about 50% in Africa (Ka et al., 2024). Similarly, NCDs remains a leading cause of death, with an age-standardized rate of 567 deaths per 100,000 people in Nigeria. This figure has surpassed deaths from infectious diseases, maternal issues, new-born conditions, and malnutrition (Bollyky et al., 2017).

This study aims to assess the prevalence and correlates of substance abuse among youths in Benin City Edo State Nigeria. A qualitative approach was applied in the thesis and content analysis was undertaken. five objectives were raised for the study. The population of the study comprised of youths residing in Oredo local government area. The data generated from the survey were analyzed by means of tables and percentages. The result of the analysis was tested at 0.05 (5%) level of significance. The findings of the study show that drug abuse negatively influences youth behaviour. The study recommend that parents should make deliberate effort to instill high moral standard and ensure they monitor the kind of friends their children hang out with in the community, as doing so will help reduce drug abuse behaviour among.