ANTIDIARRHEAL PROPERTIES OF

Traditional herbal medicine refers to the use of plants or plant material, either in crude or processed form, to treat illnesses or injuries. Presently, there is ongoing investigation into the therapeutic potential of medicinal plants with ethnomedicinal properties. The aim of this study is to evaluate the in-vitro anti-oxidants and anti-diarrheal properties of poly herbal formulated tea.(Citrus Lemon, Curcuma Longa, Zingiber Officcinale, Allium Sativum, Moringa Deifera, Syzygium aromaticum). The formulation, consisting of multiple herbal extracts, was subjected to antioxidant assays using ascorbic acid as the standard. Additionally, its effect on GIT motility was assessed using loperamide as the standard in an anti-diarrheal model induced by castor oil, with water serving as the control. Results from the antioxidant assay revealed significant antioxidant activity of
the poly-herbal formulation, comparable to that of ascorbic acid. However, in the antidiarrheal model, the formulation did not exhibit significant antidiarrheal properties when compared to the control (water) and the standard (loperamide). Interestingly, the poly-herbal formulation demonstrated a significant effect on GIT motility, indicating its potential to modulate intestinal transit time. These findings suggest that while the poly-herbal formulation lacks antidiarrheal properties, it possesses notable antioxidant activity and influences gastrointestinal motility. Further research is warranted to elucidate the mechanisms underlying its effects on GIT motility and explore its
potential therapeutic applications in gastrointestinal disorders.