FORMULATION AND EVALUATION OF A CO-PROCESSED EXCIPIENT FOR DIRECT COMPRESSION OF GLIMEPIRIDE TABLETS.
Faculty
Year of Publication
upload
Publication Type
Abstract
Co-processed excipients have been developed to enhance the performance of poorly soluble drugs like Glimepiride. Varying ratios of the API (Glimepiride) was mixed with the co-processed excipients and from the results, there was improved flowability, compressibility and disintegration properties, optimizing tablet formulation and bioavailability. Studies have demonstrated reduced lubricant sensitivity and enhanced drug release profiles. Co-processed excipients offer improved dilution potential, mechanical strength and faster manufacturing processes making co-procession a valuable advancement in pharmaceutical technology
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co-supervisor