FRUIT AQUEOUS EXTRACT

Traditional medicine encompasses manual therapies, exercises, and spiritual therapies in addition to medical therapies, theories, and practices that involve medications derived from plants, animals, and minerals. This investigation aims to assess the ability of Azanza garckeana in treating diarrhea in Swiss mice. Castor oil-induced diarrhea and gastrointestinal transit models in mice were used to assess the antidiarrheal effects of various dosages of the plant extract (25, 50, and 100 mg/kg). According to the study’s findings, the extract significantly (p < 0.05) reduced both the frequency of wet feces being defecated and the amount of feces produced overall when compared to the control group. In comparison to the untreated control, the extract triggered a substantial (p < 0.05) antimotility activity at higher doses. In conclusion, this study validated the ethnomedicinal report of Azanza garckeana as an efficacious anti-diarrhoea property, thereby required further study for compound elucidation and evaluation