EVALUATION OF ELEMENTAL ANALYSIS, TOTAL ALKALOIDS, ABTS, AMINO ACIDS PROFILE, HEAT INDUCED HAEMOLYSIS AND ANTI-DIABETIC POTENTIAL OF MORINDA CITRIFOLIA
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Abstract
This study investigates the medicinal properties of the leaf extract of Morinda Citrifolia, commonly known as Noni, with a particular focus on its anti-diabetic potential, antioxidant activity, and biochemical composition. The research encompasses an in-depth analysis of the Morinda Citrifolia extract phytochemical composition, antidiabetic activity, elemental composition, heat-induced hemoglobin inhibition, and alkaloid and amino acid profiles. After
identifying bioactive components by phytochemical screening, the extract was tested in vitro for its potential as an antidiabetic and its capacity to prevent hemoglobin denaturation. In addition to
analyzing the alkaloid and amino acid profiles, elemental analysis was used to ascertain the concentration of both beneficial and detrimental components. An inhibitory assay was used to
measure the antidiabetic action, and absorbance measurements were used to identify heat-induced hemoglobin inhibition.
The extract contained alkaloids, flavonoids, tannins, saponins, glycosides, terpenoids and phenolic chemicals, according to phytochemical screening. With a maximal inhibitory activity of 49.10%
at a dosage of 0.5 mg/mL, the antidiabetic activity demonstrated a dose-dependent rise in inhibition. Significant action was shown by the heat-induced hemoglobin inhibition, which peaked
at 84.07% at 300 mg/mL. Essential elements including calcium, magnesium, zinc, and potassium were found by elemental analysis; dangerous elements like lead and chromium were not found in
any discernible amounts. The total protein or amino acid content in the extract was 111.58840, and there was 0.2 g of total alkaloids.
Morinda Citrifolia extract has significant biological properties, such as antioxidant and antidiabetic actions, as well as the capacity to prevent hemoglobin denaturation. The extract's possible therapeutic applications are further supported by the presence of vital components and bioactive phytochemicals. The presence of protein and amino acids, however, raises the plant’s nutritional and medicinal value. These results lay the groundwork for additional research into
Morinda Citrifolia’s active ingredients and potential medical uses
identifying bioactive components by phytochemical screening, the extract was tested in vitro for its potential as an antidiabetic and its capacity to prevent hemoglobin denaturation. In addition to
analyzing the alkaloid and amino acid profiles, elemental analysis was used to ascertain the concentration of both beneficial and detrimental components. An inhibitory assay was used to
measure the antidiabetic action, and absorbance measurements were used to identify heat-induced hemoglobin inhibition.
The extract contained alkaloids, flavonoids, tannins, saponins, glycosides, terpenoids and phenolic chemicals, according to phytochemical screening. With a maximal inhibitory activity of 49.10%
at a dosage of 0.5 mg/mL, the antidiabetic activity demonstrated a dose-dependent rise in inhibition. Significant action was shown by the heat-induced hemoglobin inhibition, which peaked
at 84.07% at 300 mg/mL. Essential elements including calcium, magnesium, zinc, and potassium were found by elemental analysis; dangerous elements like lead and chromium were not found in
any discernible amounts. The total protein or amino acid content in the extract was 111.58840, and there was 0.2 g of total alkaloids.
Morinda Citrifolia extract has significant biological properties, such as antioxidant and antidiabetic actions, as well as the capacity to prevent hemoglobin denaturation. The extract's possible therapeutic applications are further supported by the presence of vital components and bioactive phytochemicals. The presence of protein and amino acids, however, raises the plant’s nutritional and medicinal value. These results lay the groundwork for additional research into
Morinda Citrifolia’s active ingredients and potential medical uses
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