EHIMWENMA STEPHANIE EDOGUN

ANTIMICROBIAL SENSITIVITY, ANTIOXIDANT ACTIVITYANDMINERAL PROFILE OF THE ETHANOLIC EXTRACTOFTHESTEM BARK OF SPONDIAS MOMBINPLANT

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Abstract
Spondias mombin is a plant used in various medicinal practices and varieties of traditional medicinal practitioners employ it as a raw material in phytomedicine. The aim of the study is to evaluate the antimicrobial sensitivity, antioxidant activity and the mineral profiling of the stem bark of Spondias mombin plant. The quantitative estimation of the phytochemical compound and the proximate analysis was done using a well-established method. The phytochemical and proximate analysis of the ethanolic extract of Spondias mombin revealed the presence of metabolites and compounds such as carbohydrate (74.404), crude protein (3.563 ±0.6), flavonoid (16.500µg/ml), saponin (17.868 µg/ml) tannin (26.346 µg/ml), alkaloid (0.8%). Theproximate analysis gave a moisture content of (38.20 ± 1.56) and ash content of (11.46±0.27). Some of the compounds identified in the phytochemical analysis were found to possess anti inflammatory, antioxidant, anti-ageing properties, protection against allergies, ache and joint
pain reduction etc. The mineral constituents were also evaluated using a well-established method: sodium (0.80), potassium (65.00), calcium (2.100), magnesium (2.460), manganese (72.85), copper (0.200), zinc (0.100), iron (1.500), nitrogen (0.570) and the ascorbic acid was analyzed using a spectrophotometer, which revealed a high vitamin C content of (1664.714). The antimicrobial activity was checked against some selected bacteria and fungi which revealed high antimicrobial activity against the selected test organisms hence Spondias mombin stem bark and its bioactive chemicals are effective in treating various illness and these studies therefore support its traditional medicinal use
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