TESTIMONY BASIL ADANNA

This study investigates the effects of Dendropanax trifidus, a traditional medicinal plant, on kidney function and morphology in Wistar rats. The aim is to evaluate the potential nephroprotective and therapeutic properties of Dendropanax trifidus extract through a series of experimental assays. Wistar rats were divided into control and treatment groups, receiving varying doses of Dendropanax trifidus extract over a predetermined period. Biochemical analyses were conducted to assess kidney function, including serum levels of creatinine, urea and electrolytes. Histological examinations of kidney tissues were performed to evaluate morphological changes and structural integrity. Results demonstrated that administration of Dendropanax trifidus significantly improvedrenal function markers in a dose-dependent manner, suggesting its potential nephroprotective effects. Histological analysis revealed a reduction in tubular injury and preserved glomerular architecture in treated rats compared to controls. These findings indicate that Dendropanax trifidus may possess beneficial effects on kidney health, potential offering a natural therapeutic option for the management of renal disorders. Further studies are warranted to elucidate the underlying mechanisms of action and to explore possible clinical applications in nephrology