LIPID PROFILE

EFFECTS OF CELL LIFE IQ ON LIVER AND LIPID PROFILE OF MALE WISTAR RATS

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Abstract
This study evaluated the subacute toxic effects of Cell Life IQ on liver function and lipid profile following 28-day repeated oral administration. Cell Life IQ is a widely used dietary supplement, but its safety profile during prolonged intake remains unclear. To assess potential toxicity, experimental animals were randomly assigned into four groups: a control group receiving distilled water and three treatment groups administered 20mg/kg( low dose) , 80mg/kg (medium doses) and 600mg/kg (high doses )of Cell Life IQ. At the end of the exposure period, blood samples were collected for biochemical analysis of liver function parameters including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total protein, and albumin. Lipid profile markers such as total cholesterol, triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) were also measured. The results showed at high dose there was a significant increase in total and direct bilirubin when compared to other groups. Also there was also increase in AST at the higher dose while ALP and ALT was not significantly unchanged at all groups. There was no significant change in the lipid profile parameters ( triglycerides, HDL, LDL etc) in all the treatment groups when compared to the control groups.
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