THE EFFECT OF PICRALIMA NITIDA AQUEOUS EXTRACT ON RENAL AND HEPATIC FUNCTIONS: A STUDY ON E/U/CREATININE AND LIVER FUNCTION BIOMARKERS IN ALBINO WISTAR RATS
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Abstract
Traditional medicine plays a crucial role in global healthcare, particularly in developing countries where plant-based remedies remain widely used. However, scientific validation of their safety and efficacy is necessary. This study examines the effects of a plant extract on liver and renal function in Wistar rats, focusing on its potential physiological impacts. Despite its traditional use, limited scientific data exist regarding its influence on hepatic and renal biomarkers.
This study investigates the impact of the extract on liver and kidney function in Wistar albino rats. A total of 40 rats were divided into control and experimental groups, with the test groups (B–E) receiving increasing doses of the extract, while Group A served as the control. The
experiment monitored changes in body weight and evaluated liver function markers, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and total bilirubin levels. Additionally, renal function was assessed through creatinine, urea, and electrolyte levels. The study aimed to determine the extract’s potential hepatotoxic or nephroprotective effects.
The findings of this study provide critical insights into the physiological effects of the plant extract, revealing its implications for liver and kidney health. The results contribute to the growing body of knowledge on the pharmacological properties of medicinal plants and their potential integration into modern therapeutic applications.
This study investigates the impact of the extract on liver and kidney function in Wistar albino rats. A total of 40 rats were divided into control and experimental groups, with the test groups (B–E) receiving increasing doses of the extract, while Group A served as the control. The
experiment monitored changes in body weight and evaluated liver function markers, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and total bilirubin levels. Additionally, renal function was assessed through creatinine, urea, and electrolyte levels. The study aimed to determine the extract’s potential hepatotoxic or nephroprotective effects.
The findings of this study provide critical insights into the physiological effects of the plant extract, revealing its implications for liver and kidney health. The results contribute to the growing body of knowledge on the pharmacological properties of medicinal plants and their potential integration into modern therapeutic applications.
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