ACUTE EFFECT OF ZINC OXIDE NANOPARTICLES ON TOTAL PROTEINS OF Clarias gariepinus EMBRYOS
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Abstract
This dissertation focused on the effects of zinc oxide nanoparticles (ZnO NPs) on the African
catfish (Clarias gariepinus) embryotoxicity. The total protein levels in the embryos of Clarias
gariepinus were determined following a standard method after exposure to different
concentrations (0.0, 0.5, 1.0, 5.0, and 10.0 µg/L) of ZnO NP for 96 hours. The results showed
that there was a minor increment in the total protein levels at the exposure of Clarias gariepinus
embryos to 0.5 µg/L ZnO NPs and a significant increase in NP concentration at 1 µg/L. The
highest level of the total protein was recorded at the 10.0 µg/L concentration exposure of the
ZnO NP to the embryos. The effect of ZnO NP increases with increasing concentration of the
ZnO NP in a dose-dependent manner. Elevated total protein levels imply that there is a possible
inflammation or infection, and this could lead to adverse developmental challenges for the fish
embryos.
catfish (Clarias gariepinus) embryotoxicity. The total protein levels in the embryos of Clarias
gariepinus were determined following a standard method after exposure to different
concentrations (0.0, 0.5, 1.0, 5.0, and 10.0 µg/L) of ZnO NP for 96 hours. The results showed
that there was a minor increment in the total protein levels at the exposure of Clarias gariepinus
embryos to 0.5 µg/L ZnO NPs and a significant increase in NP concentration at 1 µg/L. The
highest level of the total protein was recorded at the 10.0 µg/L concentration exposure of the
ZnO NP to the embryos. The effect of ZnO NP increases with increasing concentration of the
ZnO NP in a dose-dependent manner. Elevated total protein levels imply that there is a possible
inflammation or infection, and this could lead to adverse developmental challenges for the fish
embryos.
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