ADULT MALEWISTAR RATS

For centuries natural products have played a very crucial role in health care and prevention of diseases.Extracts of G. kola have been demonstrated to possess antimicrobial effects and has also been shown to possess hepatoprotective activities. The seed is used to prevent and relieve colic, chest colds and cough and can as well be used to treat headache. The nature of the spermato zoa (their vitality, motility and morphology) and the composition of seminal fluid are important for sperm function. Basic sperm analysis measures the number of spermatozoa (per unit volume and per ejaculate), motility and morphology. This study was carried out on twenty healthy adult male Wistar rats weighing between 200g to 250g. Group A was the control group. Group B was low dose administration group (250mg/kg body weight).Group C was intermediate dose administration group (500mg/kg body weight). Group D was high dose administration group (1000mg/kg body weight) The result of the statistical analysis showed that Garcinia kola caused significant increases (P < 0.05) serum FSH, testosterone and percentage of abnormal sperm cells which in conjuction with the vascular congestion noticed. There was no significant difference in total sperm count, body weight and testes weight. There was significant decrease in sperm motility and morphology.