biomarkers

CHANGES IN OXIDATIVE STRESS MARKER LEVELS IN YOUNG ADULT MALES OF DIFFERENT GENOTYPE POST FUNCTIONAL EXERCISE

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Abstract
The six-minute walk test (6MWT) is a widely-used submaximal field walking test used to evaluate functional exercise capacity. It assesses the distance an individual can walk on a flat, hard surface in six minutes and the final distance is recorded in meters. This study was aimed to investigate changes in oxidative stress marker levels in young adult males of different genotypes post functional exercise at the University of Benin. Forty-four (44) healthy young adult males aged 18-29 years were recruited for this study. Oxidative stress arises from an imbalance between elevated reactive oxygen species (ROS) and insufficient antioxidant defenses Oxidative stress marker levels were measured pre and post-test. The analysis was done at the chemical pathology laboratory of the University of Benin Teaching Hospital, Benin City. The statistical analysis was done using Graph Pad Prism statistical package Version 8.1. The standard error of mean (SEM) was used in tables and graphs to display the results. The dependent and independent variable means were compared using the student t-test. P<0.05 was accepted as significant. The results showed that there was no significant change in the oxidative stress marker levels relative to genotype.
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