Wistar rat Hematological parameters Ethnomedicinal plants

Polyherbal formulations are widely utilized across the globe and have gained increasing recognition due to their natural origin and minimal side effects. These combinations enhance therapeutic potency while reducing the required concentrations of individual herbal components. This research investigates the hematological effects of a polyherbal aqueous extract in phenyl hydrazine induced anemic Wistar rats. The plant materials were collected, processed, and formulated into the polyherbal aqueous extract. Thirty-six rats were randomly assigned into six groups: positive control, negative control, normal control, and three treatment groups receiving different doses of the extract. Variations in body and organ weights were assessed, and blood samples were analyzed for biochemical parameters. The results revealed significant differences in white blood cells, lymphocytes, mid-sized cells, granulocytes, platelets, mean platelet volume, platelet distribution width, plateletcrit, and platelet large cell ratio compared to the control groups. These findings support the ethnomedicinal use of the selected plants as anti-anemic agents and highlight their potential for further preclinical and clinical evaluation. Overall, the study suggests that the polyherbal aqueous extract may serve as a promising alternative therapy for anaemia