. E.O Igudia

The purpose of the study is to assess the knowledge and attitudes towards the guidelines for the prevention of mother-to-child transmission of HIV in Ethiope West LGA. The descriptive survey research design was adopted for this study. The population of the study comprised of two thousand, one hundred and twenty two (2,122) women of childbearing age who attended prenatal and postnatal care services between July 2023 and August 2023 at the Primary Healthcare Centres in Ethiope West Local Government Area (Delta State Primary Healthcare Development Agency, Asaba, Delta state). The sample size for this study was 229 respondents. The collected data were analysed using descriptive statistics of frequency and percentages for the research questions raised. While inferential statistics of chi-square was used to test the formulated hypothesis at 0.05 level of significance. The study concludes that while knowledge and attitudes towards PMTCT guidelines are generally high among respondents in Ethiope West LGA, there is a need for continuous education and awareness programs to maintain and improve these levels. Additionally, targeted interventions should be considered to address the gaps identified, particularly among specific age groups and educational levels. Strengthening PMTCT programs through comprehensive education and supportive attitudes can significantly reduce the risk of mother-to-child transmission of HIV, contributing to better health outcomes for mothers and their children.