LIPID PROFILE AND AQUEOUS

LIPID PROFILE AND TOXICOLOGICAL EVALUATION OF AQUEOUS AND METHANOL EXTRACTS OF Acalypha Wilkesiana LEAF IN WISTAR RATS.

Year of Publication
Publication Type
Abstract
The experiment is aimed at carrying out a toxicological study on rats given different doses of both aqueous and methanol extract of Acalypha Wilkesiana and to determine the degree of toxicity on some organs of the rats fed with both aqueous and methanol extract of Acalypha Wilkesiana. A total of seventy five male albino rats were used for the whole of the experiments. For Acute toxicity study phase one of the studies alone was carried out. For sub-acute toxicity study: The rats were placed into 4 different groups and group 1 served as the control group that was fed with pellets and water, the other groups that’s group 2 to 4 was divided into 2 sub-groups (group 2A aqueous and 2B methanol), and was given different doses of plant extracts. For 28 days, to mark the end of our sub-acute toxicological study, liver and kidney function biomarkers, electrolytes, lipid profile assays were investigated. For the acute toxicity study, it was observed that there was no visible sign of toxicity or death observed in all
the animals administered with the aqueous and methanol extract of Acalypha Wilkesiana
Supervisor(s)
co-supervisor