ADEBISI SAMUEL ADEOLUWA

This study investigated the antidiabetic and electrolyte-modulating effects of ethanol extract of Tetracera alnifolia in streptozotocin-induced diabetic Wistar rats. The extract was administered at doses of 200 mg/kg, 500 mg/kg, and 800 mg/kg, and its effects on fasting blood sugar (FBS) levels and sodium levels were evaluated. The results showed that the 500 mg/kg dose exerted a significant hypoglycemic effect, maintaining lower FBS levels over time. Additionally, the extract at 200 mg/kg and 500 mg/kg maintained sodium levels closer to the normal range. These findings suggest that the ethanol extract of Tetracera alnifolia may have therapeutic potential in the management of diabetes, particularly in regulating blood glucose and electrolyte balance.