HISTOLOGICAL ASSESSMENT OF LIVER DEVELOPMENT FOLLOWING INTRAUTERINE EXPOSURE TO CARBON TETRACHLORIDE IN WISTAR DAMS
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Abstract
The liver is the main organ where exogenous and endogenous chemicals are metabolized and finally excreted. As a consequence, hepatocytes are exposed to remarkable concentrations of these chemicals and drugs, which can lead to cell death, hepatoxicity, liver dysfunction, and even organ failure. During fetal development, the liver plays a crucial role in hematopoiesis, metabolism, and detoxification. Any disruptions or
abnormalities in liver development can have long-lasting effects on liver function and overall health.
abnormalities in liver development can have long-lasting effects on liver function and overall health.
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