Normotensives

This study aimed to investigate the effects of graded doses of Hibiscus Sabdariffa aqueous extract on intraocular pressure (IOP) and blood pressure (BP) in normotensive individuals. A total of 40 university students (22 males, 18 females) aged 18-29 years (mean age: 24.3 ± 3.20 years) participated in this study. The participants were divided into four groups: three experimental groups (A, B, C) and a control group (D), each consisting of 10 normotensive subjects. Baseline IOP and BP measurements were obtained using an iCare TA01i Tonometer and a HEM-7124 blood pressure monitor, respectively. The experimental groups received graded doses of Hibiscus Sabdariffa aqueous extract, and IOP and BP measurements were taken at 30-, 60-, 90-, and 120-minutes post-ingestion. The results showed a significant decrease in IOP in the left eye, with a statistically significant effect observed (p < 0.05), and the most substantial reduction occurred at 120 minutes post-ingestion. Additionally, the effect of Hibiscus Sabdariffa on BP was found to be dose-dependent, with a statistically significant effect observed (p < 0.05). This study recommends that potential integration of Hibiscus sabdariffa leaf aqueous extract as a complementary therapy in the management of certain ocular conditions warrants further consideration. However, additional research is needed to fully elucidate its therapeutic potential and safety profile Keywords: Hibiscus Sabdariffa, Intraocular pressure, Blood pressure and Normotensives.