DICHLOROMETHANE

Azanza garckeana also known as snot apple is an important food and medicinal plant, which serves as a good source of herbal medicine in tropical Africa. Azanza garckeana fruits were obtained from Tula, Kaltungo Local Government, Gombe State, in the North-Eastern region of Nigeria. This study was carried out in order to identify the bioactive compounds with health- promoting benefits present in the dichloromethane extract of the seeds of Azanza garckeana. To characterize diverse bioactive compounds present in the plant, the dichloromethane extract of the seeds of this fruit were subjected to GC-MS analysis. Eighteen (18) bioactive compounds were found in the seeds. According to the result, (Z)-3-(pentadec-8-en-1-yl) phenol had the highest concentration of 69.79% and the longest retention period at 17.987 minutes. This compound was found to have Anti-hyperglycemic and Antioxidant properties. The least component in the seeds extract, pentasiloxane, dodecamethyl, had a concentration of 0.35% and a retention period of 3.430 minutes. Other bioactive compounds present in the dichloromethane extract and their biological activities include; Cyclohexasiloxane, dodecamethyl- (Antibacterial and Antioxidant activities), Cyclododecane (Antimicrobial activity), Cycloheptasiloxane, tetradecamethyl- (Antioxidant and Anti-inflammatory activities), Methyl stearate (Antioxidant activity). According to the findings, Azanza garckeana (snot apple) has a lot of potential as a source of naturally occurring bioactive substances utilized as therapeutic agents in the treatment and prevention of different ailments.