PROPERTIES

BIOPHYSICAL PROPERTIES OF THE HUMAN SENSORY ORGANS; A CASE STUDY OF TNHE HUMAN SKIN

Year of Publication
Publication Type
Abstract
The skin is the largest sensory organ in the human body and is crucial for protection, regulating temperature, and sensory detection. It acts as a complex boundary between the body and the outside world, reacting to electrical impulses, physical forces, and changes in temperature. A thorough understanding of the biophysical characteristics of the skin is essential for advancements in material science, biomedical engineering, dermatology, and biomedicine. This research explores how the mechanical, thermal, and electrical properties of human skin affect its functionality. The study examines skin elasticity, viscoelastic behavior, heat transfer mechanisms, and electrodermal activity through a comprehensive review of existing studies and experimental methods. This research review explored skin elasticity, viscoelastic behavior, heat transfer, and electrodermal activity. Using nanoindentation and stress- strain analysis, it found that skin elasticity varies by body region and age, with Young's modulus decreasing as we age. Creep and stress relaxation tests confirmed the skin's viscoelastic properties. Thermal properties were assessed using infrared thermography, indicating that well-hydrated skin dissipates heat more effectively. The skin's role in thermoregulation is reinforced by studies on vasodilation and sweating. V Electrodermal activity (EDA) and skin impedance spectroscopy reveal that skin conductivity changes with moisture levels and external stimuli, serving as important indicators of emotional and physiological states. This study also explores how sensory nerves convey tactile and thermal sensations to the nervous system. The findings enhance our understanding of the skin's multifunctionality and have potential applications in medical diagnostics, wearable technology, and prosthetics, aligning with existing research in biophysics and dermatology
Supervisor(s)
co-supervisor

A NEW PARALOGISTIC-WEIBULL DISTRIBUTION: MODEL, PROPERTIES, AND APPLICATION

Year of Publication
Publication Type
Abstract
Lifetime data analysis plays a crucial role in various fields, ranging from engineering to epidemiology. In this study, we investigate the effectiveness of the Paralogistic-Weibull distribution in modeling lifetime data compared to other competing distributions such as the Weibull and Paralogistic distributions. Two datasets were analyzed: the daily number of COVID-19 infected persons in Nigeria and the survival times of patients with Head and Neck Cancer. We employed goodness-of-fit tests, including the Kolmogorov-Smirnov, Anderson-Darling, and Cramér-von Mises tests, along with discrepancy criteria such as the Akaike Information Criterion (AIC) and Bayesian Information Criterion (BIC), to evaluate the performance of the distributions. The results indicate that the ParalogisticWeibull distribution consistently outperforms the other distributions across both datasets, exhibiting higher p-values and lower discrepancy criteria values. Therefore, we conclude that the Paralogistic-Weibull distribution offers superior flexibility and accuracy in modeling lifetime data, providing valuable insights for practitioners and researchers in the field of lifetime data analysis.
Supervisor(s)
co-supervisor