ASSESSMENTOFPHARMACISTINTERVENTIONINTHE IDENTIFICATIONAND RESOLUTIONOFDRUGTHERAPY PROBLEMSAMONGHYPERTENSIVEPATIENTSATTHE UNIVERSITYOFBENINTE
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Abstract
Background: Hypertension remains a major global health concern, with a high prevalence in
Nigeria leading to significant cardiovascular morbidity. Despite the availability of effective
antihypertensive drugs, poor blood pressure control persists due to drug therapy problems
(DTPs) such as non-adherence and inappropriate therapy.
Objective: To assess the impact of pharmacist intervention in identifying and resolving drug
therapy problems among hypertensive patients at the University of Benin Teaching Hospital,
Benin City.
Method: A prospective observational study was conducted among 226 hypertensive patients
attending the Consultant Outpatient Department pharmacy. Data were collected using
structured forms based on the Pharmaceutical Care Network Europe (PCNE) classification
system. Statistical analyses were performed using SPSS software.
Results: Out of 226 participants, 60.6% had at least one DTP. The most common problem
was non-adherence (47.3%), mostly patient-related (47.3%). Pharmacist interventions were
primarily patient-level (48.2%), with counselling being the major strategy (48.2%). Patient
acceptance of interventions was 48.2%, and prescriber acceptance 14.6%. Duration of
diagnosis showed a significant relationship with DTP occurrence (p = 0.008).
Conclusion: Pharmacist interventions significantly contributed to identifying and resolving
DTPs, improving adherence, and optimizing hypertension management. Integrating
pharmacists into multidisciplinary care teams is essential for enhancing patient outcomes and
minimizing medication-related problems
Nigeria leading to significant cardiovascular morbidity. Despite the availability of effective
antihypertensive drugs, poor blood pressure control persists due to drug therapy problems
(DTPs) such as non-adherence and inappropriate therapy.
Objective: To assess the impact of pharmacist intervention in identifying and resolving drug
therapy problems among hypertensive patients at the University of Benin Teaching Hospital,
Benin City.
Method: A prospective observational study was conducted among 226 hypertensive patients
attending the Consultant Outpatient Department pharmacy. Data were collected using
structured forms based on the Pharmaceutical Care Network Europe (PCNE) classification
system. Statistical analyses were performed using SPSS software.
Results: Out of 226 participants, 60.6% had at least one DTP. The most common problem
was non-adherence (47.3%), mostly patient-related (47.3%). Pharmacist interventions were
primarily patient-level (48.2%), with counselling being the major strategy (48.2%). Patient
acceptance of interventions was 48.2%, and prescriber acceptance 14.6%. Duration of
diagnosis showed a significant relationship with DTP occurrence (p = 0.008).
Conclusion: Pharmacist interventions significantly contributed to identifying and resolving
DTPs, improving adherence, and optimizing hypertension management. Integrating
pharmacists into multidisciplinary care teams is essential for enhancing patient outcomes and
minimizing medication-related problems
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