HISTOMORPHOLOGICAL

INVESTIGATING THE HISTOMORPHOLOGICAL EFFECT OF Alstonia boonei STEM BARK EXTRACT ON THE LIVER AND KIDNEY OF WISTAR ALBINO RATS

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Abstract
Alstonia boonei, a plant species known for its medicinal properties and a tropical tree native to Africa, may exhibit protective effects on some vital organs. Various parts of the tree, including the bark, leaves, and roots, have been used in traditional medicine for their anti-inflammatory, antimicrobial, and antioxidant properties. The aim of this study is to evaluate the histomorphological effects of Alstonia boonei stem bark extract on the liver and kidney of Wistar albino rats. Thirty healthy rats were separated into groups and housed in controlled conditions. Histopathological examinations will assess potential damage or protective effects. Given Alstonia boonei's potential antioxidant and anti-inflammatory properties, it may offer benefits for liver and kidney health. The results of this study may provide insights into the potential therapeutic applications of Alstonia boonei in preventing liver and kidney damage. Some studies suggest that Alstonia boonei stem bark extract may have hepatoprotective properties, reducing liver damage and inflammation. Additionally, it may alleviate hyperlipidemia and renal malfunctions in benign prostatic hyperplasia-induced rats . Further research is needed to explore the mechanisms underlying these effects and to determine the optimal dosage for maximum protection.
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