PREVENTIVE DIABETIC EFFECTS ON STREPTOZOCIN INDUCED DIABETIC RATS AFTER ADMINISTRATION OF BI-HERBAL MIXTURE OF Ocimum gratissimum AND Murraya koenigii

Diabetes mellitus (DM) is the most common endocrine disorder, affecting over 100 million people worldwide, which accounts for approximately 6% of the global population. It is caused by either a deficiency in insulin production or the body’s inability to effectively use insulin, leading to abnormal blood glucose levels. This condition can damage multiple body systems, particularly
the blood vessels, eyes, kidneys, heart, and nerves (Ismail, 2019). Diabetes mellitus is classified into two main types: insulin dependent diabetes mellitus (IDDM, Type I) and non-insulin dependent diabetes mellitus (NIDDM, Type II). Type I diabetes is an autoimmune disorder characterized by inflammation and destruction of insulin producing cells in the pancreas, while Type II diabetes is marked by insulin resistance and impaired insulin secretion