Faculty
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Abstract
Background:Drug therapy problems(DTPs)are a major healthcare challenge which are associated with increased cost of treatment, misdiagnosis, increased length of hospitalization, decreased patient satisfaction with care and increased morbidity and mortality. Pharmacists play a crucial role in optimising medication use and improving patient outcomes within hospitals. Their clinical interventions span medication reconciliation, drug-drug interaction identification, dosage adjustments, and therapeutic optimisation.However,the extent and impact of these interventions often remain undocumented hindering both individual
pharmacist accountability and the evaluation of pharmacy services on patient care. Objectives: The primary objective of this study is to evaluate the drug therapy problem documented by clinical pharmacists at the University of Benin Teaching Hospital(UBTH) Benin between April 2015 and April 2024.Method:This is a retrospective cross-sectional study conducted in thirteen pharmacy
departments of the University of Benin Teaching Hospital(UBTH),Benin. All DTPs identified and interventions made by clinical pharmacists evidenced by documentation were extracted. Descriptive statistics were used for the analysis of clinical pharmacist interventions.The prescribers’ acceptance rate of the pharmacists' recommendation on the identified drug therapy problem was calculated by dividing the number of accepted interventions by the total number of interventions and then multiplying by 100.
Result: A total of 986 drug therapy problems were identified during the study with 48.17% of them being identified in 2023 as compared to 0% drug therapy problems in 2017. Between 2015 and 2020, only 189 DTPs were documented across the various pharmacy departments.COPD-NHIS documented the most DTPs with 135 drug therapy problems representing 13.7% v of the total DTPs documented while Main Theatre pharmacy recorded the fewest DTPs, accounting for only 1.4% (14) of the DTPs. Dosage too high is the most prevalent DTP occurring 363 times representing 36.8% whereas inappropriate adherence is the least prevalent occurring 15 times and accounting for 1.5% of the DTPs. About 22.2% (219) of these interventions were directetowards paediatrics (below 12 years) and 31.7% (313) to adults (>19 years). Antibiotics were the most affected drug occurring 249 times accounting for 25.1% of the drugs affected.It's closely followed by antihypertensives occurring 103 representing10.4%and closely followed by centrally acting drugs with 91 occurrences accounting for 9.2% of the drugs affected. About 22.1% (218) of the interventions were directed towards the males and 29.0% (286) towards the females. Of the 986 DTPs recorded, the prescribers were contacted 851 times and they accepted 847 pharmacists’ recommendations.Conclusion: Over a decade, the documented drug therapy problems (DTPs) were surprisingly low for a major teaching hospital. A review of the recorded DTPs revealed a notable proportion occurred in females, while a smaller proportion affected males, and a significant number lacked gender documentation.A significant proportion of the interventions were focused on pediatric patients under12years old, while a notable proportion was directed toward adults over 19 years old. All 7 classes of DTPs were represented with a dosage too high being the most prevalent DTP while inappropriate adherence is the least prevalent.All drug therapy problems recorded were resolved.The prescribers demonstrated a remarkably high acceptance rate of the pharmacists'recommendations for the identified drugtherapy problem, with nearly all suggested interventions being implemented, indicating a strong collaborative approach to addressing drug therapy problems
pharmacist accountability and the evaluation of pharmacy services on patient care. Objectives: The primary objective of this study is to evaluate the drug therapy problem documented by clinical pharmacists at the University of Benin Teaching Hospital(UBTH) Benin between April 2015 and April 2024.Method:This is a retrospective cross-sectional study conducted in thirteen pharmacy
departments of the University of Benin Teaching Hospital(UBTH),Benin. All DTPs identified and interventions made by clinical pharmacists evidenced by documentation were extracted. Descriptive statistics were used for the analysis of clinical pharmacist interventions.The prescribers’ acceptance rate of the pharmacists' recommendation on the identified drug therapy problem was calculated by dividing the number of accepted interventions by the total number of interventions and then multiplying by 100.
Result: A total of 986 drug therapy problems were identified during the study with 48.17% of them being identified in 2023 as compared to 0% drug therapy problems in 2017. Between 2015 and 2020, only 189 DTPs were documented across the various pharmacy departments.COPD-NHIS documented the most DTPs with 135 drug therapy problems representing 13.7% v of the total DTPs documented while Main Theatre pharmacy recorded the fewest DTPs, accounting for only 1.4% (14) of the DTPs. Dosage too high is the most prevalent DTP occurring 363 times representing 36.8% whereas inappropriate adherence is the least prevalent occurring 15 times and accounting for 1.5% of the DTPs. About 22.2% (219) of these interventions were directetowards paediatrics (below 12 years) and 31.7% (313) to adults (>19 years). Antibiotics were the most affected drug occurring 249 times accounting for 25.1% of the drugs affected.It's closely followed by antihypertensives occurring 103 representing10.4%and closely followed by centrally acting drugs with 91 occurrences accounting for 9.2% of the drugs affected. About 22.1% (218) of the interventions were directed towards the males and 29.0% (286) towards the females. Of the 986 DTPs recorded, the prescribers were contacted 851 times and they accepted 847 pharmacists’ recommendations.Conclusion: Over a decade, the documented drug therapy problems (DTPs) were surprisingly low for a major teaching hospital. A review of the recorded DTPs revealed a notable proportion occurred in females, while a smaller proportion affected males, and a significant number lacked gender documentation.A significant proportion of the interventions were focused on pediatric patients under12years old, while a notable proportion was directed toward adults over 19 years old. All 7 classes of DTPs were represented with a dosage too high being the most prevalent DTP while inappropriate adherence is the least prevalent.All drug therapy problems recorded were resolved.The prescribers demonstrated a remarkably high acceptance rate of the pharmacists'recommendations for the identified drugtherapy problem, with nearly all suggested interventions being implemented, indicating a strong collaborative approach to addressing drug therapy problems
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