This study investigates the in vitro antioxidant activity of ethanol extracts derived from Foeniculum vulgare seeds, commonly exploited for its medicinal purposes. Foeniculum vulgare is rich in bioactive compounds with potential health benefits, including

This study investigates the in vitro antioxidant activity of ethanol extracts derived from Foeniculum vulgare seeds, commonly exploited for its medicinal purposes. Foeniculum vulgare is rich in bioactive compounds with potential health benefits, including antioxidant properties. High-Performance Liquid Chromatography (HPLC) analysis was employed to identify and quantify the bioactive constituents present in the extracts. The antioxidant potential was evaluated using various in vitro assays, including 2,2-diphenyl- 1-picrylhydrazyl (DPPH) radical scavenging, ferric reducing antioxidant power (FRAP) assays, Total Antioxidant Capacity (TAC), Hydroxyl Radical Scavenging Activity, and Nitric Oxide Scavenging Ability. The results revealed significant a significant difference when compared with the standard ascorbic acid, ethanol extract of Foeniculum vulgare, presence of antioxidant activity with DPPH, FRAP and TAC assays. HPLC profiling provided valuable insights into the chemical composition of the extracts, elucidating the presence of specific antioxidant compounds. This study underscores the potential of Foeniculum vulgare seeds as a natural source of antioxidants and highlights the importance of HPLC analysis in characterizing their bioactive constituents. Further research may explore the therapeutic implications of these findings in the context of oxidative stress-related disorder.