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Abstract
Dengue fever is endemic in Nigeria and remains a significant cause of misdiagnosed febrile illnesses, particularly in children. Despite rising Aedes mosquito populations in urban centers, limited data exists on dengue prevalence among pediatric populations in Benin City. This study's aim was to determine the prevalence of dengue virus infection among febrile children attending
various medical centers in Benin City, Nigeria. A hospital-based cross-sectional study was conducted among 160 febrile children aged 1 month to 10 years attending selected healthcare facilities in Benin City. Socio-demographic data were collected using structured questionnaires. Blood samples were collected from each participants through sterile aseptic techniques and
dispensed into plain containers. The samples were spun at 3000rpm for 5 minutes to obtain the serum. The overall prevalence of dengue virus IgM antibodies was 4.4% (7/160) among the study population. IgG antibodies prevalence of 3.1% (5/160) while both IgM and IgG antibodies coinfection of 0.6% (1/160) was obtained among the study population. Seroprevalence was highest among the 3-4 years age group, followed by 1-2 years age group with the lowest prevalence found in <11 months age group. Gender and Age did not significantly influence the prevalence of dengue virus antibodies among the study population. Use of mosquito nets and
water storage methods significantly influenced the prevalence of dengue virus seroprevalence among the study population though not statistically significant. This study reveals a notable prevalence of dengue virus infection among febrile children in Benin City, highlighting the need for improved diagnostic considerations and public health surveillance in pediatric fever management.
various medical centers in Benin City, Nigeria. A hospital-based cross-sectional study was conducted among 160 febrile children aged 1 month to 10 years attending selected healthcare facilities in Benin City. Socio-demographic data were collected using structured questionnaires. Blood samples were collected from each participants through sterile aseptic techniques and
dispensed into plain containers. The samples were spun at 3000rpm for 5 minutes to obtain the serum. The overall prevalence of dengue virus IgM antibodies was 4.4% (7/160) among the study population. IgG antibodies prevalence of 3.1% (5/160) while both IgM and IgG antibodies coinfection of 0.6% (1/160) was obtained among the study population. Seroprevalence was highest among the 3-4 years age group, followed by 1-2 years age group with the lowest prevalence found in <11 months age group. Gender and Age did not significantly influence the prevalence of dengue virus antibodies among the study population. Use of mosquito nets and
water storage methods significantly influenced the prevalence of dengue virus seroprevalence among the study population though not statistically significant. This study reveals a notable prevalence of dengue virus infection among febrile children in Benin City, highlighting the need for improved diagnostic considerations and public health surveillance in pediatric fever management.
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