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Medicinal plants have been used to treat diseases all across the world for thousands of years. The methanolic extract of powdered leaves of Carica papaya, Laurus nobilis, and Gongronema latifolium were subjected to phytochemical screening and antioxidants activity assays. The presence of alkaloids, flavonoids, steroids, and tannins in methanol extract was revealed by phytochemical screening. The leaf extract of Carica papaya showed the presence of the
flavonoids, cardiac glycosides, alkaloids, tannins, phenols, steroids, terpernoids, saponnis, but quinones were absent. Laurus nobilis was found to contain flavonoids, tannins, saponins, cardiac glycosides, steroids, alkaloids, phenols, quinones but terpernoids were absent. Gongronema latifolium was found to contain tannins, saponins, terpernoids, alkaloids, quinones, but steroids, phenols, cardiac glycosides, phenols, steroids, flavonoids were absent. The EC50 value of the DPPH radical scavenging activities shows that Bay leaf (0.586± 0.049µg/ml) has the highest radical scavenging activity followed by Pawpaw leaf (0.685± 0.012µg/ml), and Utazi leaf (0.896± 0.104µg/ml). The Phosphomolybdate assay shows that Utazi (0.619±0.012 μg/ml) >Pawpaw (0.752± 0.166μg/ml) and Bay (0.816± 0.094 μg/ml). Hydrogen peroxide: Pawpaw leaf>Utazi leaf >Bay leaf respectively. Reducing power for Pawpaw leaf >Bay leaf >Utazi leaf which had the lowest value. The total flavonoid content shows that Bay leaf (0.053± 0.010mg/gQE) has the highest total flavonoids content followed by Pawpaw leaf (0.233±0.012mg/gQE) and Utazi leaf (0.051± 0.008mg/gQE). The total phenolic content shows that Bay leaf0.145± 0.021mg/gGAE, have the highest total phenolic content followed by Pawpaw leaf 0.055±0.015mg/gGAE, and Utazi leaf 0.041±0.003mg/gGAE. These results show a non-statistical significant difference (p>0.05) in antioxidants activities of Pawpaw leaf, Bay leaf, Utazi leafs and standard antioxidant activity. It also shows that leaves of utazi, pawpaw and bay possess significant phytochemicals and antioxidant activity.
flavonoids, cardiac glycosides, alkaloids, tannins, phenols, steroids, terpernoids, saponnis, but quinones were absent. Laurus nobilis was found to contain flavonoids, tannins, saponins, cardiac glycosides, steroids, alkaloids, phenols, quinones but terpernoids were absent. Gongronema latifolium was found to contain tannins, saponins, terpernoids, alkaloids, quinones, but steroids, phenols, cardiac glycosides, phenols, steroids, flavonoids were absent. The EC50 value of the DPPH radical scavenging activities shows that Bay leaf (0.586± 0.049µg/ml) has the highest radical scavenging activity followed by Pawpaw leaf (0.685± 0.012µg/ml), and Utazi leaf (0.896± 0.104µg/ml). The Phosphomolybdate assay shows that Utazi (0.619±0.012 μg/ml) >Pawpaw (0.752± 0.166μg/ml) and Bay (0.816± 0.094 μg/ml). Hydrogen peroxide: Pawpaw leaf>Utazi leaf >Bay leaf respectively. Reducing power for Pawpaw leaf >Bay leaf >Utazi leaf which had the lowest value. The total flavonoid content shows that Bay leaf (0.053± 0.010mg/gQE) has the highest total flavonoids content followed by Pawpaw leaf (0.233±0.012mg/gQE) and Utazi leaf (0.051± 0.008mg/gQE). The total phenolic content shows that Bay leaf0.145± 0.021mg/gGAE, have the highest total phenolic content followed by Pawpaw leaf 0.055±0.015mg/gGAE, and Utazi leaf 0.041±0.003mg/gGAE. These results show a non-statistical significant difference (p>0.05) in antioxidants activities of Pawpaw leaf, Bay leaf, Utazi leafs and standard antioxidant activity. It also shows that leaves of utazi, pawpaw and bay possess significant phytochemicals and antioxidant activity.
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